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esProc Joins Text files and Generates a Computed Column

There are two tab-separated structured text files. chr column in AssociatedMarkers.txt is the logical foreign key pointing to Chr column in DiseaseMarkers.txt. We want to create a new structured text file, in which one column comes from AssociatedMarkers.txt’s snps_BCG24 column and the other is a computed column that will get its values through the following algorithm: If a value of AssociatedMarkers.txt’s hg19pos column falls within the startLoc and endLoc in DiseaseMarkers.txt, then output it as inLocus; otherwise output it as an empty string. Selections of the two files are as follows:

AssociatedMarkers.txt

esProc_text_computed_column_1

DiseaseMarkers.txt

esProc_text_computed_column_2

esProc approach:

        

A

1

=file(“/Users/Me/AssociatedMarkers.txt”).import@t()

2

=file(“/Users/Me/DiseaseMarkers.txt”).import@t()

3

=join(A1,chr;A2,Chr)

4

=A3.new(_1.snps_BCG24,if(in(_1.hg19pos,_2.startLoc:_2.endLoc),”inLocus”))

A1,A2: Import the files into memory. @t means importing column names at the same time.

A3: Perform join operation. Result is as follows: 

esProc_text_computed_column_4

A4: Retrieve desired columns from A3. _1.hg19pos column corresponds AssociatedMarkers.txt’s hg19pos column. The final result is as follows:

esProc_text_computed_column_5

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